Mushijo

The main character, Hinako Momotsuki, is a high school girl who loves the anime "Puri Puri" and devotes all her energy into otaku activities. However, in actuality, when she unites with a mysterious "Maji" centipede life form, she becomes a distorted hero who saves people. Now she fights both to save the town assailed by "Maji" and to protect her unrequited crush, Himoru-senpai.

(Source: Kodansha, translated)